Publications

2021-present

Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons.
Guoqiang Wang, Ryan J Guasp, Sangeena Salam, Edward Chuang, Andrés Morera, Anna J Smart, David Jimenez, Sahana Shekhar, Emily Friedman, Ilija Melentijevic, Ken C Nguyen, David H Hall, Barth D Grant, Monica Driscoll.
Elife. 2024 Sep 10;13:RP95443. doi: 10.7554/eLife.95443.

RABR-1, an atypical Rab-related GTPase, cell-nonautonomously restricts somatosensory dendrite branching.
Christopher J Salazar, Carlos A Diaz-Balzac, Yu Wang, Maisha Rahman, Barth D Grant, Hannes E Bülow.
Genetics. 2024 Oct 7;228(2):iyae113. doi: 10.1093/genetics/iyae113.

LRK-1/LRRK2 and AP-3 regulate trafficking of synaptic vesicle precursors through active zone protein SYD-2/Liprin-α.
Sravanthi S P Nadiminti, Shirley B Dixit, Neena Ratnakaran, Anushka Deb, Sneha Hegde, Sri Padma Priya Boyanapalli, Sierra Swords, Barth D Grant, Sandhya P Koushika.
PLoS Genet. 2024 May 9;20(5):e1011253. doi: 10.1371/journal.pgen.1011253. eCollection 2024 May.

Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons.
Guoqiang Wang, Ryan Guasp, Sangeena Salam, Edward Chuang, Andrés Morera, Anna J Smart, David Jimenez, Sahana Shekhar, Emily Friedman, Ilija Melentijevic, Ken C Nguyen, David H Hall, Barth D Grant, Monica Driscoll.
bioRxiv [Preprint]. 2024 Jun 10:2023.11.13.565361. doi: 10.1101/2023.11.13.565361.

A conserved requirement for RME-8/DNAJC13 in neuronal autophagic lysosome reformation.
Sierra B Swords, Nuo Jia, Anne Norris, Jil Modi, Qian Cai, Barth D Grant.
Autophagy. 2024 Apr;20(4):792-808. doi: 10.1080/15548627.2023.2269028. Epub 2023 Nov 9.

Syndapin and GTPase RAP-1 control endocytic recycling via RHO-1 and non-muscle myosin II.
Wilmer R Rodriguez-Polanco, Anne Norris, Agustin B Velasco, Adenrele M Gleason, Barth D Grant.
Curr Biol. 2023 Nov 20;33(22):4844-4856.e5. doi: 10.1016/j.cub.2023.09.051. Epub 2023 Oct 12.

Macrocephaly and developmental delay caused by missense variants in RAB5C.
Klaas Koop, Weimin Yuan, Federico Tessadori, Wilmer R Rodriguez-Polanco, Jeremy Grubbs, Bo Zhang, Matt Osmond, Gail Graham, Sarah Sawyer, Erin Conboy, Francesco Vetrini, Kayla Treat, Rafal Płoski, Victor Murcia Pienkowski, Anna Kłosowska, Elizabeth Fieg, Joel Krier, Coralie Mallebranche, Ziegler Alban, Kimberly A Aldinger, Deborah Ritter, Ellen Macnamara, Bonnie Sullivan, John Herriges, Joseph T Alaimo, Catherine Helbig, Colin A Ellis, Clare van Eyk, Jozef Gecz, Daniel Farrugia, Ikeoluwa Osei-Owusu, Lesley Adès, Marie-Jose van den Boogaard, Sabine Fuchs, Jeroen Bakker, Karen Duran, Zachary D Dawson, Anika Lindsey, Huiyan Huang, Dustin Baldridge, Gary A Silverman, Barth D Grant, David Raizen, Undiagnosed Diseases Network, Gijs van Haaften, Stephen C Pak, Holger Rehmann, Tim Schedl, Peter van Hasselt.
Hum Mol Genet. 2023 Oct 17;32(21):3063-3077. doi: 10.1093/hmg/ddad130.

Intermediate filaments associate with aggresome-like structures in proteostressed C. elegans neurons and influence large vesicle extrusions as exophers.
Meghan Lee Arnold, Jason Cooper, Rebecca Androwski, Sohil Ardeshna, Ilija Melentijevic, Joelle Smart, Ryan J Guasp, Ken C Q Nguyen, Ge Bai, David H Hall, Barth D Grant, Monica Driscoll.
Nat Commun. 2023 Jul 24;14(1):4450. doi: 10.1038/s41467-023-39700-1.

SPE-51, a sperm-secreted protein with an immunoglobulin-like domain, is required for fertilization in C. elegans.
Xue Mei, Katherine A Maniates, A'maya Looper, Amber R Krauchunas, Marina Druzhinina, Sunny Dharia, Julie Ni, Gunasekaran Singaravelu, Sam Guoping Gu, Diane C Shakes, Barth D Grant, Andrew W Singson.
Curr Biol. 2023 Jul 24;33(14):3048-3055.e6. doi: 10.1016/j.cub.2023.06.029. Epub 2023 Jul 14.

Conserved NIMA kinases regulate multiple steps of endocytic trafficking.
Braveen B Joseph, Naava Naslavsky, Shaonil Binti, Sylvia Conquest, Lexi Robison, Ge Bai, Rafael O Homer, Barth D Grant, Steve Caplan, David S Fay.
PLoS Genet. 2023 Apr 26;19(4):e1010741. doi: 10.1371/journal.pgen.1010741. eCollection 2023 Apr.

A Conserved Requirement for RME-8/DNAJC13 in Neuronal Autolysosome Reformation.
Sierra Swords, Nuo Jia, Anne Norris, Jil Modi, Qian Cai, Barth D Grant.
bioRxiv [Preprint]. 2023 Feb 28:2023.02.27.530319. doi: 10.1101/2023.02.27.530319.

Syndapin Regulates the RAP-1 GTPase to Control Endocytic Recycling via RHO-1 and Non-Muscle Myosin II.
Wilmer R Rodriguez-Polanco, Anne Norris, Agustin B Velasco, Adenrele M Gleason, Barth D Grant.
bioRxiv [Preprint]. 2023 Feb 28:2023.02.27.530328. doi: 10.1101/2023.02.27.530328.

Active zone protein SYD-2/Liprin-alpha acts downstream of LRK-1/LRRK2 to regulate polarized trafficking of synaptic vesicle precursors through clathrin adaptor protein complexes.
Sravanthi S P Nadiminti, Shirley B Dixit, Neena Ratnakaran, Sneha Hegde, Sierra Swords, Barth D Grant, Sandhya P Koushika.
bioRxiv [Preprint]. 2023 Feb 26:2023.02.26.530068. doi: 10.1101/2023.02.26.530068.

Large vesicle extrusions from C. elegans neurons are consumed and stimulated by glial-like phagocytosis activity of the neighboring cell.
Yu Wang, Meghan Lee Arnold, Anna Joelle Smart, Guoqiang Wang, Rebecca J Androwski, Andres Morera, Ken C Q Nguyen, Peter J Schweinsberg, Ge Bai, Jason Cooper, David H Hall, Monica Driscoll, Barth D Grant.
Elife. 2023 Mar 2;12:e82227. doi: 10.7554/eLife.82227.

Mutagenesis and structural modeling implicate RME-8 IWN domains as conformational control points.
Anne Norris, Collin T McManus, Simon Wang, Ruochen Ying, Barth D Grant.
PLoS Genet. 2022 Oct 24;18(10):e1010296. doi: 10.1371/journal.pgen.1010296. eCollection 2022 Oct.

Stress increases in exopher-mediated neuronal extrusion require lipid biosynthesis, FGF, and EGF RAS/MAPK signaling.
Jason F Cooper, Ryan J Guasp, Meghan Lee Arnold, Barth D Grant, Monica Driscoll.
Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2101410118. doi: 10.1073/pnas.2101410118.

The CATP-8/P5A-type ATPase functions in multiple pathways during neuronal patterning.
Leo T H Tang, Meera Trivedi, Jenna Freund, Christopher J Salazar, Maisha Rahman, Nelson J Ramirez-Suarez, Garrett Lee, Yu Wang, Barth D Grant, Hannes E Bülow.
PLoS Genet. 2021 Jul 1;17(7):e1009475. doi: 10.1371/journal.pgen.1009475. eCollection 2021 Jul.

2011-2020

Quantitative Approaches for Scoring in vivo Neuronal Aggregate and Organelle Extrusion in Large Exopher Vesicles in C. elegans.
Meghan Lee Arnold, Jason Cooper, Barth D Grant, Monica Driscoll.
J Vis Exp. 2020 Sep 18;(163):10.3791/61368. doi: 10.3791/61368.

Endosomal microdomains: Formation and function.
Anne Norris, Barth D Grant.
Curr Opin Cell Biol. 2020 Aug;65:86-95. doi: 10.1016/j.ceb.2020.02.018. Epub 2020 Apr 1.

Control of clathrin-mediated endocytosis by NIMA family kinases.
Braveen B Joseph, Yu Wang, Phil Edeen, Vladimir Lažetić, Barth D Grant, David S Fay.
PLoS Genet. 2020 Feb 18;16(2):e1008633. doi: 10.1371/journal.pgen.1008633. eCollection 2020 Feb.

Tetraspanins TSP-12 and TSP-14 function redundantly to regulate the trafficking of the type II BMP receptor in Caenorhabditis elegans.
Zhiyu Liu, Herong Shi, Anthony K Nzessi, Anne Norris, Barth D Grant, Jun Liu.
Proc Natl Acad Sci U S A. 2020 Feb 11;117(6):2968-2977. doi: 10.1073/pnas.1918807117. Epub 2020 Jan 27.

SLC17A6/7/8 Vesicular Glutamate Transporter Homologs in Nematodes.
Esther Serrano-Saiz, Merly C Vogt, Sagi Levy, Yu Wang, Karolina K Kaczmarczyk, Xue Mei, Ge Bai, Andrew Singson, Barth D Grant, Oliver Hobert.
Genetics. 2020 Jan;214(1):163-178. doi: 10.1534/genetics.119.302855. Epub 2019 Nov 27.

Revealing Functional Crosstalk between Distinct Bioprocesses through Reciprocal Functional Tests of Genetically Interacting Genes.
Dan Chen, Wei Xu, Yu Wang, Yongshen Ye, Yue Wang, Miao Yu, Jinghu Gao, Jielin Wei, Yiming Dong, Honghua Zhang, Xin Fu, Ke Ma, Hui Wang, Zhenrong Yang, Jie Zhou, Wenqing Cheng, Shu Wang, Juan Chen, Barth D Grant, Chad L Myers, Anbing Shi, Tian Xia.
Cell Rep. 2019 Nov 26;29(9):2646-2658.e5. doi: 10.1016/j.celrep.2019.10.076.

A novel requirement for ubiquitin-conjugating enzyme UBC-13 in retrograde recycling of MIG-14/Wntless and Wnt signaling.
Junbing Zhang, Jinchao Liu, Anne Norris, Barth D Grant, Xiaochen Wang.
Mol Biol Cell. 2018 Aug 15;29(17):2098-2112. doi: 10.1091/mbc.E17-11-0639. Epub 2018 Jun 21.

The recycling endosome protein RAB-10 promotes autophagic flux and localization of the transmembrane protein ATG-9.
N J Palmisano, N Rosario, M Wysocki, M Hong, B Grant, A Meléndez.
Autophagy. 2017 Oct 3;13(10):1742-1753. doi: 10.1080/15548627.2017.1356976. Epub 2017 Sep 5.

SNX-1 and RME-8 oppose the assembly of HGRS-1/ESCRT-0 degradative microdomains on endosomes.
Anne Norris, Prasad Tammineni, Simon Wang, Julianne Gerdes, Alexandra Murr, Kelvin Y Kwan, Qian Cai, Barth D Grant.
Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E307-E316. doi: 10.1073/pnas.1612730114. Epub 2017 Jan 4.

Syndapin/SDPN-1 is required for endocytic recycling and endosomal actin association in the C. elegans intestine.
Adenrele M Gleason, Ken C Q Nguyen, David H Hall, Barth D Grant.
Mol Biol Cell. 2016 Sep 14;27(23):3746-56. doi: 10.1091/mbc.E16-02-0116. Online ahead of print.

Linking Gene Expression in the Intestine to Production of Gametes Through the Phosphate Transporter PITR-1 in Caenorhabditis elegans.
Zita Balklava, Navin D Rathnakumar, Shilpa Vashist, Peter J Schweinsberg, Barth D Grant.
Genetics. 2016 Sep;204(1):153-62. doi: 10.1534/genetics.116.188532. Epub 2016 Jul 22.

RAB-10 Promotes EHBP-1 Bridging of Filamentous Actin and Tubular Recycling Endosomes.
Peixiang Wang, Hang Liu, Yu Wang, Ou Liu, Jing Zhang, Adenrele Gleason, Zhenrong Yang, Hui Wang, Anbing Shi, Barth D Grant.
PLoS Genet. 2016 Jun 6;12(6):e1006093. doi: 10.1371/journal.pgen.1006093. eCollection 2016 Jun.

Basolateral Endocytic Recycling Requires RAB-10 and AMPH-1 Mediated Recruitment of RAB-5 GAP TBC-2 to Endosomes.
Ou Liu, Barth D Grant.
PLoS Genet. 2015 Sep 22;11(9):e1005514. doi: 10.1371/journal.pgen.1005514. eCollection 2015.

In vivo analysis of recycling endosomes in Caenorhabditis elegans.
Anbing Shi, Barth D Grant.
Methods Cell Biol. 2015;130:181-98. doi: 10.1016/bs.mcb.2015.04.001. Epub 2015 Jun 11.

A TOCA/CDC-42/PAR/WAVE functional module required for retrograde endocytic recycling.
Zhiyong Bai, Barth D Grant.
Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):E1443-52. doi: 10.1073/pnas.1418651112. Epub 2015 Mar 9.

C. elegans as a model for membrane traffic.
Ken Sato, Anne Norris, Miyuki Sato, Barth D Grant.
WormBook. 2014 Apr 25:1-47. doi: 10.1895/wormbook.1.77.2.

BMP signaling requires retromer-dependent recycling of the type I receptor.
Ryan J Gleason, Adenrele M Akintobi, Barth D Grant, Richard W Padgett.
Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2578-83. doi: 10.1073/pnas.1319947111. Epub 2014 Feb 3.

C. elegans gene transformation by microparticle bombardment.
Peter J Schweinsberg, Barth D Grant.
WormBook. 2013 Dec 30:1-10. doi: 10.1895/wormbook.1.166.1.

Phagocytic receptor signaling regulates clathrin and epsin-mediated cytoskeletal remodeling during apoptotic cell engulfment in C. elegans.
Qian Shen, Bin He, Nan Lu, Barbara Conradt, Barth D Grant, Zheng Zhou.
Development. 2013 Aug;140(15):3230-43. doi: 10.1242/dev.093732.

SH3 interactome conserves general function over specific form.
Xiaofeng Xin, David Gfeller, Jackie Cheng, Raffi Tonikian, Lin Sun, Ailan Guo, Lianet Lopez, Alevtina Pavlenco, Adenrele Akintobi, Yingnan Zhang, Jean-François Rual, Bridget Currell, Somasekar Seshagiri, Tong Hao, Xinping Yang, Yun A Shen, Kourosh Salehi-Ashtiani, Jingjing Li, Aaron T Cheng, Dryden Bouamalay, Adrien Lugari, David E Hill, Mark L Grimes, David G Drubin, Barth D Grant, Marc Vidal, Charles Boone, Sachdev S Sidhu, Gary D Bader.
Mol Syst Biol. 2013;9:652. doi: 10.1038/msb.2013.9.

AP2 hemicomplexes contribute independently to synaptic vesicle endocytosis.
Mingyu Gu, Qiang Liu, Shigeki Watanabe, Lin Sun, Gunther Hollopeter, Barth D Grant, Erik M Jorgensen.
Elife. 2013 Mar 5;2:e00190. doi: 10.7554/eLife.00190.

Interactions between Rab and Arf GTPases regulate endosomal phosphatidylinositol-4,5-bisphosphate during endocytic recycling.
Anbing Shi, Barth D Grant.
Small GTPases. 2013 Apr-Jun;4(2):106-9. doi: 10.4161/sgtp.23477. Epub 2013 Feb 7.

RAB-5 and RAB-10 cooperate to regulate neuropeptide release in Caenorhabditis elegans.
Nikhil Sasidharan, Marija Sumakovic, Mandy Hannemann, Jan Hegermann, Jana F Liewald, Christian Olendrowitz, Sabine Koenig, Barth D Grant, Silvio O Rizzoli, Alexander Gottschalk, Stefan Eimer.
Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18944-9. doi: 10.1073/pnas.1203306109. Epub 2012 Oct 25.

RAB-10-GTPase-mediated regulation of endosomal phosphatidylinositol-4,5-bisphosphate.
Anbing Shi, Ou Liu, Sabine Koenig, Riju Banerjee, Carlos Chih-Hsiung Chen, Stefan Eimer, Barth D Grant.
Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):E2306-15. doi: 10.1073/pnas.1205278109. Epub 2012 Aug 6.

CED-10/Rac1 regulates endocytic recycling through the RAB-5 GAP TBC-2.
Lin Sun, Ou Liu, Jigar Desai, Farhad Karbassi, Marc-André Sylvain, Anbing Shi, Zheng Zhou, Christian E Rocheleau, Barth D Grant.
PLoS Genet. 2012;8(7):e1002785. doi: 10.1371/journal.pgen.1002785. Epub 2012 Jul 12.

RAB-5 controls the cortical organization and dynamics of PAR proteins to maintain C. elegans early embryonic polarity.
Vincent Hyenne, Thierry Tremblay-Boudreault, Ramraj Velmurugan, Barth D Grant, Dinah Loerke, Jean-Claude Labbé.
PLoS One. 2012;7(4):e35286. doi: 10.1371/journal.pone.0035286. Epub 2012 Apr 24.

RAB-6.2 and the retromer regulate glutamate receptor recycling through a retrograde pathway.
Donglei Zhang, Nora R Isack, Doreen R Glodowski, Jie Liu, Carlos Chih-Hsiung Chen, X Z Shawn Xu, Barth D Grant, Christopher Rongo.
J Cell Biol. 2012 Jan 9;196(1):85-101. doi: 10.1083/jcb.201104141. Epub 2012 Jan 2.

The P4-ATPase TAT-5 inhibits the budding of extracellular vesicles in C. elegans embryos.
Ann M Wehman, Corey Poggioli, Peter Schweinsberg, Barth D Grant, Jeremy Nance.
Curr Biol. 2011 Dec 6;21(23):1951-9. doi: 10.1016/j.cub.2011.10.040. Epub 2011 Nov 17.

Essential roles of snap-29 in C. elegans.
Junsu Kang, Zhiyong Bai, Matthew H Zegarek, Barth D Grant, Junho Lee.
Dev Biol. 2011 Jul 1;355(1):77-88. doi: 10.1016/j.ydbio.2011.04.013. Epub 2011 Apr 22.

The Atg6/Vps30/Beclin 1 ortholog BEC-1 mediates endocytic retrograde transport in addition to autophagy in C. elegans.
Alexander Ruck, John Attonito, Kelly T Garces, Lizbeth Núnez, Nicholas J Palmisano, Zahava Rubel, Zhiyong Bai, Ken C Q Nguyen, Lei Sun, Barth D Grant, David H Hall, Alicia Meléndez.
Autophagy. 2011 Apr;7(4):386-400. doi: 10.4161/auto.7.4.14391. Epub 2011 Apr 1.

1999-2010

EHBP-1 functions with RAB-10 during endocytic recycling in Caenorhabditis elegans.
Anbing Shi, Carlos Chih-Hsiung Chen, Riju Banerjee, Doreen Glodowski, Anjon Audhya, Christopher Rongo, Barth D Grant.
Mol Biol Cell. 2010 Aug 15;21(16):2930-43. doi: 10.1091/mbc.E10-02-0149. Epub 2010 Jun 23.

Regulated lysosomal trafficking as a mechanism for regulating GABAA receptor abundance at synapses in Caenorhabditis elegans.
Kathleen M Davis, Brianne L Sturt, Andrew J Friedmann, Janet E Richmond, Jean-Louis Bessereau, Barth D Grant, Bruce A Bamber.
Mol Cell Neurosci. 2010 Aug;44(4):307-17. doi: 10.1016/j.mcn.2010.04.002. Epub 2010 Apr 18.

AMPH-1/Amphiphysin/Bin1 functions with RME-1/Ehd1 in endocytic recycling.
Saumya Pant, Mahak Sharma, Kruti Patel, Steve Caplan, Chavela M Carr, Barth D Grant.
Nat Cell Biol. 2009 Dec;11(12):1399-410. doi: 10.1038/ncb1986. Epub 2009 Nov 15.

EGG-4 and EGG-5 Link Events of the Oocyte-to-Embryo Transition with Meiotic Progression in C. elegans.
Jean M Parry, Nathalie V Velarde, Ariel J Lefkovith, Matthew H Zegarek, Julie S Hang, Jonathan Ohm, Richard Klancer, Rika Maruyama, Marina K Druzhinina, Barth D Grant, Fabio Piano, Andrew Singson.
Curr Biol. 2009 Nov 3;19(20):1752-7. doi: 10.1016/j.cub.2009.09.015.

Analysis of articulation between clathrin and retromer in retrograde sorting on early endosomes.
Vincent Popoff, Gonzalo A Mardones, Siau-Kun Bai, Valérie Chambon, Danièle Tenza, Patricia V Burgos, Anbing Shi, Philippe Benaroch, Sylvie Urbé, Christophe Lamaze, Barth D Grant, Graça Raposo, Ludger Johannes.
Traffic. 2009 Dec;10(12):1868-80. doi: 10.1111/j.1600-0854.2009.00993.x. Epub 2009 Oct 5.

Requirements for F-BAR proteins TOCA-1 and TOCA-2 in actin dynamics and membrane trafficking during Caenorhabditis elegans oocyte growth and embryonic epidermal morphogenesis.
Chiara Giuliani, Flavia Troglio, Zhiyong Bai, Falshruti B Patel, Adriana Zucconi, Maria Grazia Malabarba, Andrea Disanza, Theresia B Stradal, Giuseppe Cassata, Stefano Confalonieri, Jeffrey D Hardin, Martha C Soto, Barth D Grant, Giorgio Scita.
PLoS Genet. 2009 Oct;5(10):e1000675. doi: 10.1371/journal.pgen.1000675. Epub 2009 Oct 2.

Regulation of endosomal clathrin and retromer-mediated endosome to Golgi retrograde transport by the J-domain protein RME-8.
Anbing Shi, Lin Sun, Riju Banerjee, Michael Tobin, Yinhua Zhang, Barth D Grant.
EMBO J. 2009 Nov 4;28(21):3290-302. doi: 10.1038/emboj.2009.272. Epub 2009 Sep 17.

Pathways and mechanisms of endocytic recycling.
Barth D Grant, Julie G Donaldson.
Nat Rev Mol Cell Biol. 2009 Sep;10(9):597-608. doi: 10.1038/nrm2755.

Differential requirements for clathrin in receptor-mediated endocytosis and maintenance of synaptic vesicle pools.
Ken Sato, Glen G Ernstrom, Shigeki Watanabe, Robby M Weimer, Chih-Hsiung Chen, Miyuki Sato, Ayesha Siddiqui, Erik M Jorgensen, Barth D Grant.
Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1139-44. doi: 10.1073/pnas.0809541106. Epub 2009 Jan 16.

The JIP3 scaffold protein UNC-16 regulates RAB-5 dependent membrane trafficking at C. elegans synapses.
Heather M Brown, Heather A Van Epps, Alexandr Goncharov, Barth D Grant, Yishi Jin.
Dev Neurobiol. 2009 Feb 1-15;69(2-3):174-90. doi: 10.1002/dneu.20690.

Coordinated regulation of AP2 uncoating from clathrin-coated vesicles by rab5 and hRME-6.
Sophia Semerdjieva, Barry Shortt, Emma Maxwell, Sukhdeep Singh, Paul Fonarev, Jonathan Hansen, Giampietro Schiavo, Barth D Grant, Elizabeth Smythe.
J Cell Biol. 2008 Nov 3;183(3):499-511. doi: 10.1083/jcb.200806016.

Mechanisms of EHD/RME-1 protein function in endocytic transport.
Barth D Grant, Steve Caplan.
Traffic. 2008 Dec;9(12):2043-52. doi: 10.1111/j.1600-0854.2008.00834.x. Epub 2008 Oct 14.

Rab11 is required for synchronous secretion of chondroitin proteoglycans after fertilization in Caenorhabditis elegans.
Miyuki Sato, Barth D Grant, Akihiro Harada, Ken Sato.
J Cell Sci. 2008 Oct 1;121(Pt 19):3177-86. doi: 10.1242/jcs.034678. Epub 2008 Sep 2.

Meiotic maturation: receptor trafficking is the key.
Julie S Hang, Barth D Grant, Andrew Singson.
Curr Biol. 2008 May 20;18(10):R416-R418. doi: 10.1016/j.cub.2008.03.033.

Caenorhabditis elegans num-1 negatively regulates endocytic recycling.
Lars Nilsson, Barbara Conradt, Anne-Françoise Ruaud, Carlos Chih-Hsiung Chen, Julia Hatzold, Jean-Louis Bessereau, Barth D Grant, Simon Tuck.
Genetics. 2008 May;179(1):375-87. doi: 10.1534/genetics.108.087247.

Regulation of endocytic recycling by C. elegans Rab35 and its regulator RME-4, a coated-pit protein.
Miyuki Sato, Ken Sato, Willisa Liou, Saumya Pant, Akihiro Harada, Barth D Grant.
EMBO J. 2008 Apr 23;27(8):1183-96. doi: 10.1038/emboj.2008.54. Epub 2008 Mar 20.

Intracellular trafficking.
Barth D Grant, Miyuki Sato.
WormBook. 2006 Jan 21:1-9. doi: 10.1895/wormbook.1.77.1.

A novel requirement for C. elegans Alix/ALX-1 in RME-1-mediated membrane transport.
Anbing Shi, Saumya Pant, Zita Balklava, Carlos Chih-Hsiung Chen, Vanesa Figueroa, Barth D Grant.
Curr Biol. 2007 Nov 20;17(22):1913-24. doi: 10.1016/j.cub.2007.10.045. Epub 2007 Nov 8.

EGG-3 regulates cell-surface and cortex rearrangements during egg activation in Caenorhabditis elegans.
Rika Maruyama, Nathalie V Velarde, Richard Klancer, Scott Gordon, Pavan Kadandale, Jean M Parry, Julie S Hang, Jacob Rubin, Allison Stewart-Michaelis, Peter Schweinsberg, Barth D Grant, Fabio Piano, Asako Sugimoto, Andrew Singson.
Curr Biol. 2007 Sep 18;17(18):1555-60. doi: 10.1016/j.cub.2007.08.011.

RAB-10 regulates glutamate receptor recycling in a cholesterol-dependent endocytosis pathway.
Doreen R Glodowski, Carlos Chih-Hsiung Chen, Henry Schaefer, Barth D Grant, Christopher Rongo.
Mol Biol Cell. 2007 Nov;18(11):4387-96. doi: 10.1091/mbc.e07-05-0486. Epub 2007 Aug 29.

Genome-wide analysis identifies a general requirement for polarity proteins in endocytic traffic.
Zita Balklava, Saumya Pant, Hanna Fares, Barth D Grant.
Nat Cell Biol. 2007 Sep;9(9):1066-73. doi: 10.1038/ncb1627. Epub 2007 Aug 19.

Dynamic regulation of caveolin-1 trafficking in the germ line and embryo of Caenorhabditis elegans.
Ken Sato, Miyuki Sato, Anjon Audhya, Karen Oegema, Peter Schweinsberg, Barth D Grant.
Mol Biol Cell. 2006 Jul;17(7):3085-94. doi: 10.1091/mbc.e06-03-0211. Epub 2006 May 3.

Rab10 regulates membrane transport through early endosomes of polarized Madin-Darby canine kidney cells.
Clifford M Babbey, Nahid Ahktar, Exing Wang, Carlos Chih-Hsiung Chen, Barth D Grant, Kenneth W Dunn.
Mol Biol Cell. 2006 Jul;17(7):3156-75. doi: 10.1091/mbc.e05-08-0799. Epub 2006 Apr 26.

The regulation of endocytosis by kinases: cell biology meets genomics.
Zita Balklava, Barth D Grant.
Genome Biol. 2005;6(13):245. doi: 10.1186/gb-2005-6-13-245. Epub 2006 Jan 3.

RAB-10 is required for endocytic recycling in the Caenorhabditis elegans intestine.
Carlos Chih-Hsiung Chen, Peter J Schweinsberg, Shilpa Vashist, Darren P Mareiniss, Eric J Lambie, Barth D Grant.
Mol Biol Cell. 2006 Mar;17(3):1286-97. doi: 10.1091/mbc.e05-08-0787. Epub 2006 Jan 4.

The egg surface LDL receptor repeat-containing proteins EGG-1 and EGG-2 are required for fertilization in Caenorhabditis elegans.
Pavan Kadandale, Allison Stewart-Michaelis, Scott Gordon, Jacob Rubin, Richard Klancer, Peter Schweinsberg, Barth D Grant, Andrew Singson.
Curr Biol. 2005 Dec 20;15(24):2222-9. doi: 10.1016/j.cub.2005.10.043.

The ins and outs of endocytic transport.
Barth D Grant, Anjon Audhya.
Nat Cell Biol. 2005 Dec;7(12):1151-4. doi: 10.1038/ncb1205-1051.

EHD proteins associate with syndapin I and II and such interactions play a crucial role in endosomal recycling.
Anne Braun, Roser Pinyol, Regina Dahlhaus, Dennis Koch, Paul Fonarev, Barth D Grant, Michael M Kessels, Britta Qualmann.
Mol Biol Cell. 2005 Aug;16(8):3642-58. doi: 10.1091/mbc.e05-01-0076. Epub 2005 Jun 1.

Caenorhabditis elegans RME-6 is a novel regulator of RAB-5 at the clathrin-coated pit.
Miyuki Sato, Ken Sato, Paul Fonarev, Chih-Jen Huang, Willisa Liou, Barth D Grant.
Nat Cell Biol. 2005 Jun;7(6):559-69. doi: 10.1038/ncb1261. Epub 2005 May 15.

Genetic analysis of lysosomal trafficking in Caenorhabditis elegans.
Greg J Hermann, Lena K Schroeder, Caroline A Hieb, Aaron M Kershner, Beverley M Rabbitts, Paul Fonarev, Barth D Grant, James R Priess.
Mol Biol Cell. 2005 Jul;16(7):3273-88. doi: 10.1091/mbc.e05-01-0060. Epub 2005 Apr 20.

ATP binding regulates oligomerization and endosome association of RME-1 family proteins.
Dong-won Lee, Xiaohong Zhao, Sarah Scarselletta, Peter J Schweinsberg, Evan Eisenberg, Barth D Grant, Lois E Greene.
J Biol Chem. 2005 Apr 29;280(17):17213-20. doi: 10.1074/jbc.M412751200. Epub 2005 Feb 13.

Caenorhabditis elegans functional orthologue of human protein h-mucolipin-1 is required for lysosome biogenesis.
Sebastian Treusch, Sarah Knuth, Susan A Slaugenhaupt, Ehud Goldin, Barth D Grant, Hanna Fares.
Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4483-8. doi: 10.1073/pnas.0400709101. Epub 2004 Mar 15.

Rme-1 regulates the recycling of the cystic fibrosis transmembrane conductance regulator.
John A Picciano, Nadia Ameen, Barth D Grant, Neil A Bradbury.
Am J Physiol Cell Physiol. 2003 Nov;285(5):C1009-18. doi: 10.1152/ajpcell.00140.2003. Epub 2003 Jul 2.

Genetic analysis of the myotubularin family of phosphatases in Caenorhabditis elegans.
Yingzi Xue, Hanna Fares, Barth Grant, Zhai Li, Ann M Rose, Scott G Clark, Edward Y Skolnik.
J Biol Chem. 2003 Sep 5;278(36):34380-6. doi: 10.1074/jbc.M303259200. Epub 2003 Jun 4.

Functional genomic maps in Caenorhabditis elegans.
Barth D Grant, Hilary A Wilkinson.
Curr Opin Cell Biol. 2003 Apr;15(2):206-12. doi: 10.1016/s0955-0674(03)00014-0.

Deciphering endocytosis in Caenorhabditis elegans.
Hanna Fares, Barth Grant.
Traffic. 2002 Jan;3(1):11-9. doi: 10.1034/j.1600-0854.2002.30103.x.

Immuno-EM localization of GFP-tagged yolk proteins in C. elegans using microwave fixation.
M C Paupard, A Miller, B Grant, D Hirsh, D H Hall.
J Histochem Cytochem. 2001 Aug;49(8):949-56. doi: 10.1177/002215540104900803.

RME-8, a conserved J-domain protein, is required for endocytosis in Caenorhabditis elegans.
Y Zhang, B Grant, D Hirsh.
Mol Biol Cell. 2001 Jul;12(7):2011-21. doi: 10.1091/mbc.12.7.2011.

Distribution and transport of cholesterol in Caenorhabditis elegans.
V Matyash, C Geier, A Henske, S Mukherjee, D Hirsh, C Thiele, B Grant, F R Maxfield, T V Kurzchalia.
Mol Biol Cell. 2001 Jun;12(6):1725-36. doi: 10.1091/mbc.12.6.1725.

Rme-1 regulates the distribution and function of the endocytic recycling compartment in mammalian cells.
S X Lin, B Grant, D Hirsh, F R Maxfield.
Nat Cell Biol. 2001 Jun;3(6):567-72. doi: 10.1038/35078543.

Evidence that RME-1, a conserved C. elegans EH-domain protein, functions in endocytic recycling.
B Grant, Y Zhang, M C Paupard, S X Lin, D H Hall, D Hirsh.
Nat Cell Biol. 2001 Jun;3(6):573-9. doi: 10.1038/35078549.

Caenorhabditis elegans auxilin: a J-domain protein essential for clathrin-mediated endocytosis in vivo.
T Greener, B Grant, Y Zhang, X Wu, L E Greene, D Hirsh, E Eisenberg.
Nat Cell Biol. 2001 Feb;3(2):215-9. doi: 10.1038/35055137.

Receptor-mediated endocytosis in the Caenorhabditis elegans oocyte.
B Grant, D Hirsh.
Mol Biol Cell. 1999 Dec;10(12):4311-26. doi: 10.1091/mbc.10.12.4311.

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